Healthier Corneas: A Patient Case of Fuch’s Endothelial Dystrophy

Several months ago, a 74 year-old female presented with symptoms of blurred vision, sometimes-painful foreign body sensation, and frequent tearing while reading. Her ocular history is positive for Fuch's Endothelial Dystrophy and was treated by a combination of Muro-128 ointment hs, and Muro 128 solution b.i.d. daily. She applies non-preserved artificial tears prn, which provides temporary relief for her discomfort. As an avid reader, she was seeking relief to pursue one of her favorite activities and better quality of life. Initial examination results included:

Restoring Corneal Clarity: Cryopreserved Amniotic Membrane and Stromal HSV

A 45 year-old gentleman was referred to me for HSV keratitis. Over the course of a six to eight year period, the patient had at least 10 recurrent stromal herpetic episodes that he could recall. He had been a police officer for over 15 years, and because of his vision, he didn’t feel safe at nighttime and in dim lit conditions. Due to his condition, he was at risk of having to resort to a desk job permanently or possibly leaving his career altogether.

Study Demonstrates Cryopreserved Amniotic Membrane Graft Reduces Recurrence After Pterygium Surgery


We recently issued a press release on study findings, published in Cornea, 2017, showing that the use of cryopreserved amniotic membrane reduces recurrence rates after pterygium surgery.

In this retrospective review, 556 eyes representing 535 patients (291 males 244 females), who had pterygium excision (527 primary, 29 recurrent) were treated with adjunctive cryopreserved amniotic membrane (Amniograft®, Bio-Tissue, Inc. Miami FL). After 17.3 ± 0.8 months (range 6-74 months), corneal recurrence occurred in only 20 eyes (3.6%) and conjunctival recurrence in 12 (2.2%) eyes, for a total recurrence rate of 5.8%.

Impacting a patient’s quality of life – A PROKERA case study


I love what I do, and one of my greatest accomplishments is knowing that I truly impacted a patient’s quality of life. This was the case with one of my patients, a 45 year-old male who works using his computer all day – he also happens to only have one eye. About two years ago, he came to see me and was extremely distraught because he could no longer see his computer without his eye watering and burning. He had moderate glaucoma and was also a steroid responder, meaning we couldn’t give him a standard steroid to help with his symptoms without compromising his glaucoma.

First Study to Demonstrate Corneal Nerve Regeneration in Patients with Dry Eye Disease with the Use of PROKERA


At the recent American Academy of Ophthalmology Meeting in New Orleans, I presented on results of “Corneal Nerve Regeneration after Self-Retained Cryopreserved Amniotic Membrane in Dry Eye Disease” recently published in The Journal of Ophthalmology, 2017 (John, et al.). This study is the first study to show that cryopreserved amniotic membrane is correlated with corneal nerve regeneration in patients with dry eye disease (DED).

Ocular Surface Regeneration in Dry Eye Disease: New Article and Case Study


For patients with chronic dry eye disease causing corneal conditions such as SPK or filamentary keratitis, PROKERA® offers a viable option for immediate intervention as a powerful anti-inflammatory with the long-lasting benefit of regenerative healing.

An Account Representative’s Perspective: Five Key Things I Learned from Being Treated with PROKERA


As an account representative for Bio-Tissue, I look forward to visiting with doctors and staff and talking about the benefits of PROKERA. However, when I recently became a patient, I learned even more about the benefits of this biologic corneal bandage with cryopreserved amniotic membrane. This experience not only helped heal my ocular surface, but also provided valuable information I can pass on to doctors and staff.

Ways to Educate our Dry Eye Patients and Make Them More at Ease


Our practice has always had a strong focus on cataract surgery, and from its inception has been at the forefront of treating patients with dry eye disease (DED). Early on, we realized the importance of having a healthy ocular surface for our patients prior to surgery. As such, all of us within the practice pay particular attention when treating patients with DED. We are very fortunate to have the most up-to-date equipment and tools available to help these patients.

"Why Intervene/5 D's” Reference Guide Now Available Online


To support doctors using PROKERA and inform others who may be interested in implementing Bio-Tissue’s biologic corneal bandage device in your practice, we recently made our "Why Intervene/5 D's" reference guide available to everyone online. This handy guide provides a quick reference to various indications where PROKERA provides clinical value, and we received such positive feedback to the print version that we decided to offer it electronically.

A Protocol for Use of PROKERA after Corneal Collagen Cross-Linking


With the Federal Drug Administration (FDA) approval of corneal collagen cross-linking (CXL) (Avedro, April 2016) for the treatment of progressive keratoconus, we can expect to see a high volume of these procedures being done by corneal specialists. Although the disease is considered rare, which according to the National Eye Institute (NEI) affects approximately one in every 2,000 Americans, the disease can lead to blindness if not treated. As we know, the surgical technique for performing CXL that is FDA-approved for use in the U.S. at this time is epithelium-off (epi-off, Dresden protocol).